Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling.

Lipoicmethylenedioxyphenol Reduces Experimental Atherosclerosis through Activation of Nrf2 Signaling.

OBJECTIVE:Oxidative stress is implicated in the pathogenesis of atherosclerosis, and Nrf2 is the transcriptional factor central in cellular antioxidant responses. In the present study, we investigate the effect of a dihydrolipoic acid derivative lipoicmethylenedioxyphenol (LMDP) on the progression o...

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Bibliographic Details
Main Authors: Zhekang Ying, Minjie Chen, Xiaoyun Xie, Xiaoke Wang, Nisharahmed Kherada, Rajagopal Desikan, Georgeta Mihai, Patrick Burns, Qinghua Sun, Sanjay Rajagopalan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4747573?pdf=render

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http://europepmc.org/articles/PMC4747573?pdf=render

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