The impact of hypoxia-inducible factors in the pathogenesis of kidney diseases: a link through cell metabolism

Kidneys are sensitive to disturbances in oxygen homeostasis. Hypoxia and activation of the hypoxia-inducible factor (HIF) pathway alter the expression of genes involved in the metabolism of renal and immune cells, interfering with their functioning. Whether the transcriptional activity of HIF protec...

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Bibliographic Details
Main Authors: Orestes Foresto-Neto, Ana Ruth Paolinetti Alves da Silva, Marcella Cipelli, Fernanda Paula Roncon Santana-Novelli, Niels Olsen Saraiva Camara
Format: Article
Language:English
Published: The Korean Society of Nephrology 2023-09-01
Series:Kidney Research and Clinical Practice
Subjects:
Online Access:http://krcp-ksn.org/upload/pdf/j-krcp-23-012.pdf