Biotin-cGMP and -cAMP are able to permeate through the gap junctions of some amacrine cells in the mouse retina despite their large size

Gap junctions transmit electrical signals in neurons and serve metabolic coupling and chemical communication. Gap junctions are made of intercellular channels with large pores, allowing ions and small molecules to permeate. In the mammalian retina, intercellular coupling fulfills many vital function...

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Bibliographic Details
Main Authors: Chunxu Yuan, Luca Gerhards, Ilia A. Solov’yov, Karin Dedek
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Ophthalmology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fopht.2023.1334602/full