Male rat leukocyte population dynamics predict a window for intervention in aging

Male rat leukocyte population dynamics predict a window for intervention in aging

Many age-associated changes in the human hematopoietic system have been reproduced in murine models; however, such changes have not been as robustly explored in rats despite the fact these larger rodents are more physiologically similar to humans. We examined peripheral blood of male F344 rats rangi...

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Bibliographic Details
Main Authors: Hagai Yanai, Christopher Dunn, Bongsoo Park, Christopher Coletta, Ross A McDevitt, Taylor McNeely, Michael Leone, Robert P Wersto, Kathy A Perdue, Isabel Beerman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
blood composition
aging
methylation
hematopoiesis
flow cytometry
intervention timepoint
Online Access:https://elifesciences.org/articles/76808

Internet

https://elifesciences.org/articles/76808

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