Is C-type natriuretic peptide regulated by a feedback loop? A study on systemic and local autoregulatory effect.
C-type natriuretic peptide (CNP) is a pivotal enhancer of endochondral bone growth and is expected to be a therapeutic reagent for impaired skeletal growth. Although we showed that CNP stimulates bone growth as a local regulator in the growth plate via the autocrine/paracrine system, CNP is abundant...
Glavni autori: | , , , , , , , |
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Format: | Članak |
Jezik: | English |
Izdano: |
Public Library of Science (PLoS)
2020-01-01
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Serija: | PLoS ONE |
Online pristup: | https://doi.org/10.1371/journal.pone.0240023 |