RUNX3 regulates the susceptibility against EGFR-targeted non-small cell lung cancer therapy using 47Sc-conjugated cetuximab

Abstract Background Radioimmunotherapy with cetuximab and conjugates with various radioisotopes is a feasible treatment option for different tumor models. Scandium-47 (47Sc), one of several β−-particle-emitting radioisotopes, displays favorable physical and chemical properties for conjugation to mon...

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Bibliographic Details
Main Authors: Da-Mi Kim, So-Young Lee, Jae-Cheong Lim, Eun-Ha Cho, Ul-Jae Park
Format: Article
Language:English
Published: BMC 2023-07-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-023-11161-1