Ginsenoside Rh1 Prevents Migration and Invasion through Mitochondrial ROS-Mediated Inhibition of STAT3/NF-κB Signaling in MDA-MB-231 Cells

Ginsenoside Rh1 Prevents Migration and Invasion through Mitochondrial ROS-Mediated Inhibition of STAT3/NF-κB Signaling in MDA-MB-231 Cells

Breast cancer (BC) a very common cancer in women worldwide. Triple negative breast cancer (TNBC) has been shown to have a poor prognosis with a high level of tumor metastatic spread. Here, the inhibitory effects of ginsenoside-Rh1 (Rh1) on BC metastasis, and its underlying signaling pathway in TNBC...

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Bibliographic Details
Main Authors: Yujin Jin, Diem Thi Ngoc Huynh, Chang-Seon Myung, Kyung-Sun Heo
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
metastasis
ginsenoside Rh1
mitochondrial ROS
STAT3
NF-κB
triple-negative breast cancer cells
Online Access:https://www.mdpi.com/1422-0067/22/19/10458

Internet

https://www.mdpi.com/1422-0067/22/19/10458

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