Whole-Genome Analysis of De Novo Somatic Point Mutations Reveals Novel Mutational Biomarkers in Pancreatic Cancer

Whole-Genome Analysis of De Novo Somatic Point Mutations Reveals Novel Mutational Biomarkers in Pancreatic Cancer

It is now known that at least 10% of samples with pancreatic cancers (PC) contain a causative mutation in the known susceptibility genes, suggesting the importance of identifying cancer-associated genes that carry the causative mutations in high-risk individuals for early detection of PC. In this st...

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Bibliographic Details
Main Authors: Amin Ghareyazi, Amir Mohseni, Hamed Dashti, Amin Beheshti, Abdollah Dehzangi, Hamid R. Rabiee, Hamid Alinejad-Rokny
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
pancreatic cancer
cancer subtype identification
somatic point mutations
genotype and phenotype characterization
therapeutic targets
personalized medicine
Online Access:https://www.mdpi.com/2072-6694/13/17/4376

Internet

https://www.mdpi.com/2072-6694/13/17/4376

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