Etodolac Fortified Sodium Deoxycholate Stabilized Zein Nanoplatforms for Augmented Repositioning Profile in Human Hepatocellular Carcinoma: Assessment of Bioaccessibility, Anti-Proliferation, Pro-Apoptosis and Oxidant Potentials in HepG2 Cells

Etodolac Fortified Sodium Deoxycholate Stabilized Zein Nanoplatforms for Augmented Repositioning Profile in Human Hepatocellular Carcinoma: Assessment of Bioaccessibility, Anti-Proliferation, Pro-Apoptosis and Oxidant Potentials in HepG2 Cells

This work aimed to enhance the purposing profile of Etodolac (ETD) in Human Hepatocellular Carcinoma (HCC) HepG2 cells using sodium deoxycholate stabilized zein nanospheres (ETD-SDZN NSs). ETD-SDZN NSs were formulated using the nan-precipitation method and were characterized, in particular, in terms...

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Bibliographic Details
Main Authors: Ahmed K. Kammoun, Maha A. Hegazy, Alaa Khedr, Zuhier Ahmed Awan, Maan T. Khayat, Majid Mohammad Al-Sawahli
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
repurposing
apoptosis
etodolac
zein
HepG2
hepatocellular carcinoma
Online Access:https://www.mdpi.com/1424-8247/15/8/916

Internet

https://www.mdpi.com/1424-8247/15/8/916

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