Stochastic modelling of tyrosine kinase inhibitor rotation therapy in chronic myeloid leukaemia

Stochastic modelling of tyrosine kinase inhibitor rotation therapy in chronic myeloid leukaemia

Abstract Background Resistance towards targeted cancer treatments caused by single nucleotide variations is a major issue in many malignancies. Currently, there are a number of available drugs for chronic myeloid leukaemia (CML), which are overcome by different sets of mutations. The main aim of thi...

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Bibliographic Details
Main Authors: H. Jonathan G. Lindström, Astrid S. de Wijn, Ran Friedman
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Cancer
Subjects:
Chronic myeloid leukaemia
Drug rotation
Treatment Simulation
Targeted therapy
Stochastic modelling
Online Access:http://link.springer.com/article/10.1186/s12885-019-5690-5

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http://link.springer.com/article/10.1186/s12885-019-5690-5

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