Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G‐Quadruplex

Joint Efforts of Replicative Helicase and SSB Ensure Inherent Replicative Tolerance of G‐Quadruplex

Abstract G‐quadruplex (G4) is a four‐stranded noncanonical DNA structure that has long been recognized as a potential hindrance to DNA replication. However, how replisomes effectively deal with G4s to avoid replication failure is still obscure. Here, using single‐molecule and ensemble approaches, th...

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Bibliographic Details
Main Authors: Lijuan Guo, Yanling Bao, Yilin Zhao, Zhiyun Ren, Lulu Bi, Xia Zhang, Cong Liu, Xi‐Miao Hou, Michelle D. Wang, Bo Sun
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:Advanced Science
Subjects:
DNA replication
G‐quadruplex
helicase
polymerase
single molecule
SSB
Online Access:https://doi.org/10.1002/advs.202307696

Internet

https://doi.org/10.1002/advs.202307696

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