Co-evolution based machine-learning for predicting functional interactions between human genes
With the rise in number of eukaryotic species being fully sequenced, large scale phylogenetic profiling can give insights on gene function, Here, the authors describe a machine-learning approach that integrates co-evolution across eukaryotic clades to predict gene function and functional interaction...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-021-26792-w |