Induction of Multiple Drug Transporters by Efavirenz

Efavirenz, an important component of human immunodeficiency virus 1 (HIV-1) therapy, causes substantial drug interactions as an inducer of cytochromes and the transporter ABCB1. So far its effect on the expression of other transporters is unknown. We therefore investigated the effect of long-term ex...

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Bibliographic Details
Main Authors: Johanna Weiss, Melanie Herzog, Sonja König, Caroline Henrike Storch, Nahal Ketabi-Kiyanvash, Walter Emil Haefeli
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319312794