Paeonol Attenuates Atherosclerosis by Inhibiting Vascular Smooth Muscle Cells Senescence via SIRT1/P53/TRF2 Signaling Pathway

Paeonol Attenuates Atherosclerosis by Inhibiting Vascular Smooth Muscle Cells Senescence via SIRT1/P53/TRF2 Signaling Pathway

Atherosclerosis is a chronic inflammatory disease leading to various vascular diseases. Vascular smooth muscle cell (VSMC) senescence promotes atherosclerotic inflammation and the formation of plaque necrosis core, in part through telomere damage mediated by a high-fat diet. Our previous research fo...

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Bibliographic Details
Main Authors: Min Zhou, Xiaolin Ma, Menglong Gao, Hongfei Wu, Yarong Liu, Xiaoyan Shi, Min Dai
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
paeonol
atherosclerosis
vascular smooth muscle cells
cell senescence
SIRT1
Online Access:https://www.mdpi.com/1420-3049/29/1/261

Internet

https://www.mdpi.com/1420-3049/29/1/261

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