The Transcription Factor ThPOK Regulates ILC3 Lineage Homeostasis and Function During Intestinal Infection

The Transcription Factor ThPOK Regulates ILC3 Lineage Homeostasis and Function During Intestinal Infection

Innate lymphoid cells (ILCs) have been identified as a heterogeneous population of lymphocytes that mirrors the cytokine and transcriptional profile of adaptive T cells. The dynamic balance between key transcription factors determines the heterogeneity, plasticity, and functions of ILC subsets. The...

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Bibliographic Details
Main Authors: Xianzhi Gao, Xin Shen, Kuai Liu, Chenyu Lu, Ying Fan, Qianying Xu, Xiaoyu Meng, Shenghui Hong, Zhengwei Huang, Xia Liu, Linrong Lu, Lie Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
ILC3s
homeostasis
transcription factor
ThPOK
mucosa
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.939033/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.939033/full

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