4535 Development of a Mouse Model to study interactions between parental history of alcohol use and early life adversity on behavioral and neurobiological development of offspring

OBJECTIVES/GOALS: Individuals with a family history of alcoholism (FH+) are more likely to develop an alcohol use disorder than those with no such history. Early life adversity has a high coincidence with FH+ making pathogenic studies difficult in clinical studies. Here, we developed a mouse model t...

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Bibliographic Details
Main Authors: Grace Porter, Juan Morales, Roslyn Valdespino, Ashley Acheson, Jason O’Connor
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120000618/type/journal_article