PNPLA6/NTE, an Evolutionary Conserved Phospholipase Linked to a Group of Complex Human Diseases

Patatin-like phospholipase domain-containing protein 6 (PNPLA6), originally called Neuropathy Target Esterase (NTE), belongs to a family of hydrolases with at least eight members in mammals. PNPLA6/NTE was first identified as a key factor in Organophosphate-induced delayed neuropathy, a degenerative...

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Bibliographic Details
Main Author: Doris Kretzschmar
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/12/4/284