The human asparaginase enzyme (ASPG) inhibits growth in leukemic cells.

The human protein ASPG is an enzyme with a putative antitumor activity. We generated in bacteria and then purified a recombinant GST-ASPG protein that we used to characterize the biochemical and cytotoxic properties of the human ASPG. We demonstrated that ASPG possesses asparaginase and PAF acetylhy...

Full description

Bibliographic Details
Main Authors: Stefania Belviso, Rodolfo Iuliano, Rosario Amato, Nicola Perrotti, Miranda Menniti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5443537?pdf=render