Rapid syntheses of N-fused heterocycles via acyl-transfer in heteroaryl ketones

Heteroaryl ketones are ubiquitous molecular scaffolds but seldom used as synthetic precusors. Here, the authors develop an acyl transfer-annulation to convert heteroaryl ketones to N-fused heterocycles, which are prevalent in bioactive molecules.

Bibliographic Details
Main Authors: Dan Ye, Hong Lu, Yi He, Zhaojing Zheng, Jinghao Wu, Hao Wei
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31063-3