Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease

Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease

Abstract Background The clinical features of Alzheimer’s disease (AD) vary substantially depending on whether the onset of cognitive deficits is early or late. The amount and distribution patterns of tau pathology are thought to play a key role in the clinical characteristics of AD, which spreads th...

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Bibliographic Details
Main Authors: Wha Jin Lee, Hanna Cho, Min Seok Baek, Han-Kyeol Kim, Jae Hoon Lee, Young Hoon Ryu, Chul Hyoung Lyoo, Joon-Kyung Seong
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Tau
Amyloid
Positron emission tomography
Network community
Online Access:https://doi.org/10.1186/s13195-022-01061-0

Internet

https://doi.org/10.1186/s13195-022-01061-0

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