Metabolic Response to Stress by the Immature Right Ventricle Exposed to Chronic Pressure Overload

Metabolic Response to Stress by the Immature Right Ventricle Exposed to Chronic Pressure Overload

Background The right ventricle exposed to chronic pressure overload exhibits hypertrophy and decompensates when exposed to stress. We hypothesize that impaired ability to increase myocardial oxidative flux through pyruvate dehydrogenase leads to hypertrophied right ventricular (RV) dysfunction when...

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Bibliographic Details
Main Authors: Masaki Kajimoto, Muhammad Nuri, Nancy G. Isern, Isabelle Robillard‐Frayne, Christine Des Rosiers, Michael A. Portman
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
congenital heart disease
myocardial metabolism
pressure overload
right ventricle
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.013169

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.119.013169

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