Distribution of PLGA-modified nanoparticles in 3D cell culture models of hypo-vascularized tumor tissue

Distribution of PLGA-modified nanoparticles in 3D cell culture models of hypo-vascularized tumor tissue

Abstract Background Advanced stage cancer treatments are often invasive and painful—typically comprised of surgery, chemotherapy, and/or radiation treatment. Low transport efficiency during systemic chemotherapy may require high chemotherapeutic doses to effectively target cancerous tissue, resultin...

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Bibliographic Details
Main Authors: Lee B. Sims, Maya K. Huss, Hermann B. Frieboes, Jill M. Steinbach-Rankins
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Nanobiotechnology
Subjects:
Nanoparticles
Cell penetrating peptide (CPP)
Cervical cancer
Nanoparticle transport
Tumor vascularization
3D cell culture
Online Access:http://link.springer.com/article/10.1186/s12951-017-0298-x

Internet

http://link.springer.com/article/10.1186/s12951-017-0298-x

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