Circadian dependency of microglial heme oxygenase-1 expression and inflammation determine neuronal injury in hemorrhagic stroke

Circadian dependency of microglial heme oxygenase-1 expression and inflammation determine neuronal injury in hemorrhagic stroke

Abstract Background The heme oxygenase-1 (HO-1) enzyme pathway is of crucial importance in the removal of toxic blood components and regulation of neuroinflammation following hemorrhagic stroke. Although a circadian pattern dependency in the incidence and severity of hemorrhagic stroke exists, it is...

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Bibliographic Details
Main Authors: Luise Henrich, Iva Kiessling, Matti Steimer, Sibylle Frase, Sandra Kaiser, Nils Schallner
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Inflammation
Subjects:
Circadian rhythm
Carbon Monoxide
Heme Oxygenase
Microglia
Phagocytosis
Brain Hemorrhage
Online Access:https://doi.org/10.1186/s12950-023-00371-w

Internet

https://doi.org/10.1186/s12950-023-00371-w

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