Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea

Analysis of clinical and genomic profiles of therapy-related myeloid neoplasm in Korea

Abstract Background Therapy-related myeloid neoplasm (T-MN) rarely occurs among cancer survivors, and was characterized by poor prognosis. T-MN has germline predisposition in a considerable proportion. Here, clinical characteristics and germline/somatic variant profiles in T-MN patients were investi...

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Main Authors: Jiwon Yun, Hyojin Song, Sung-Min Kim, Soonok Kim, Seok Ryun Kwon, Young Eun Lee, Dajeong Jeong, Jae Hyeon Park, Sunghoon Kwon, Hongseok Yun, Dong Soon Lee
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Human Genomics
Subjects:
Therapy-related myeloid neoplasm
Next-generation sequencing
Germline predisposition
Somatic mutation
Online Access:https://doi.org/10.1186/s40246-023-00458-8

Internet

https://doi.org/10.1186/s40246-023-00458-8

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