PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling

Context The phosphorylation of signal transducer and activator of transcription protein 3 (STAT3) is up-regulated in glioblastoma (GBM) cells and is regulated by protein tyrosine phosphatase receptor type M (PTPRM). Fibronectin-1 (FN1) is also reported to be up-regulated in GBM. Objective We explore...

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Bibliographic Details
Main Authors: Jian Song, Di Zhao, Guozhu Sun, Jiankai Yang, Zhongqiang Lv, Baohua Jiao
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2021.1944220