Mineralocorticoid hypertension and hypokalaemia induced by posaconazole

We describe severe hypokalaemia and hypertension due to a mineralocorticoid effect in a patient with myelodysplastic syndrome taking posaconazole as antifungal prophylaxis. Two distinct mechanisms due to posaconazole are identified: inhibition of 11β hydroxylase leading to the accumulation of the mi...

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Bibliographic Details
Main Authors: Charlotte Boughton, David Taylor, Norman Taylor, Benjamin C Whitelaw, Lea Ghataore
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Echo Research and Practice
Online Access:https://www.edmcasereports.com/articles/endocrinology-diabetes-and-metabolism-case-reports/10.1530/EDM-17-0157