In-vitro NET-osis induced by COVID-19 sera is associated to severe clinical course in not vaccinated patients and immune-dysregulation in breakthrough infection

In-vitro NET-osis induced by COVID-19 sera is associated to severe clinical course in not vaccinated patients and immune-dysregulation in breakthrough infection

Abstract Since neutrophil extracellular traps formation (NET-osis) can be assessed indirectly by treating healthy neutrophils with blood-derived fluids from patients and then measuring the NETs response, we designed a pilot study to convey high-dimensional cytometry of peripheral blood immune cells...

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Bibliographic Details
Main Authors: Alessandra Romano, Nunziatina Laura Parrinello, Martina Barchitta, Rosy Manuele, Fabrizio Puglisi, Andrea Maugeri, Alessandro Barbato, Anna Maria Triolo, Cesarina Giallongo, Daniele Tibullo, Lucia La Ferla, Ciro Botta, Sergio Siragusa, Carmelo Iacobello, Arturo Montineri, Giovanni Li Volti, Antonella Agodi, Giuseppe Alberto Palumbo, Francesco Di Raimondo
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11157-0

Internet

https://doi.org/10.1038/s41598-022-11157-0

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