SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection

SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of deaths, posing a substantial threat to global public health. Viruses evolve different strategies to antagonize or evade host immune responses. While ectopic expression of SARS-CoV-2 accessory protein ORF6 bl...

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Bibliographic Details
Main Authors: Minghua Li, Kasirajan Ayyanathan, Mark Dittmar, Jesse Miller, Iulia Tapescu, Jae Seung Lee, Marisa E. McGrath, Yong Xue, Sanjay Vashee, David C. Schultz, Matthew B. Frieman, Sara Cherry
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
SARS-CoV-2
ORF6
interferon
antagonism
Online Access:https://journals.asm.org/doi/10.1128/mbio.01194-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01194-23

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