Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function

Abstract Current interest in Foxp3+ T-regulatory (Treg) cells as therapeutic targets in transplantation is largely focused on their harvesting pre-transplant, expansion and infusion post-transplantation. An alternate strategy of pharmacologic modulation of Treg function using histone/protein deacety...

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Bibliographic Details
Main Authors: Jianbing Huang, Liqing Wang, Satinder Dahiya, Ulf H. Beier, Rongxiang Han, Arabinda Samanta, Joel Bergman, Eduardo M. Sotomayor, Edward Seto, Alan P. Kozikowski, Wayne W. Hancock
Format: Article
Language:English
Published: Nature Portfolio 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-09211-3

Internet

https://doi.org/10.1038/s41598-017-09211-3

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