FXR controls duodenogastric reflux-induced gastric inflammation through negatively regulating ER stress-associated TNXIP/NLPR3 inflammasome

FXR controls duodenogastric reflux-induced gastric inflammation through negatively regulating ER stress-associated TNXIP/NLPR3 inflammasome

Summary: Duodenogastric reflux (DGR) is closely associated with gastric inflammation and tumorigenesis; however, the precise mechanism is unclear. Hence, we aim to clarify this molecular mechanism and design an effective therapeutic strategy based on it. The present study found that DGR induced TXNI...

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Manylion Llyfryddiaeth
Prif Awduron: Junhui Yu, Chenye Zhao, Pengwei Zhao, Mingchao Mu, Xiaopeng Li, Jianbao Zheng, Xuejun Sun
Fformat: Erthygl
Iaith:English
Cyhoeddwyd: Elsevier 2024-03-01
Cyfres:iScience
Pynciau:
Molecular Biology
Immunology
Cell Biology
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2589004224003390

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http://www.sciencedirect.com/science/article/pii/S2589004224003390

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