The critical role of mode of action studies in kinetoplastid drug discovery

Understanding the target and mode of action of compounds identified by phenotypic screening can greatly facilitate the process of drug discovery and development. Here, we outline the tools currently available for target identification against the neglected tropical diseases, human African trypanosom...

Full description

Bibliographic Details
Main Authors: Alan H. Fairlamb, Susan Wyllie
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Drug Discovery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fddsv.2023.1185679/full