Examining Topoisomers of a Snake-Venom-Derived Peptide for Improved Antimicrobial and Antitumoral Properties

Examining Topoisomers of a Snake-Venom-Derived Peptide for Improved Antimicrobial and Antitumoral Properties

Ctn[15-34], the C-terminal section of crotalicidin (Ctn), a cathelicidin from a South American pit viper, is an antimicrobial and antitumoral peptide with remarkably longer stability in human serum than the parent Ctn. In this work, a set of topoisomers of both Ctn and Ctn[15-34], including the retr...

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Bibliographic Details
Main Authors: Adam Carrera-Aubesart, Sira Defaus, Clara Pérez-Peinado, Daniel Sandín, Marc Torrent, Maria Ángeles Jiménez, David Andreu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
antimicrobial peptides
snake venom
crotalicidin
Ctn[15-34]
enantio-, retro-, and retroenantio peptides
topoisomer peptides
Online Access:https://www.mdpi.com/2227-9059/10/9/2110

Internet

https://www.mdpi.com/2227-9059/10/9/2110

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