Understanding the Mechanism of Translocation of Adenylate Cyclase Toxin across Biological Membranes

Adenylate cyclase toxin (ACT) is one of the principal virulence factors secreted by the whooping cough causative bacterium Bordetella pertussis, and it has a critical role in colonization of the respiratory tract and establishment of the disease. ACT targets phagocytes via binding to the CD11b/CD18...

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Bibliographic Details
Main Authors: Helena Ostolaza, César Martín, David González-Bullón, Kepa B. Uribe, Asier Etxaniz
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/9/10/295