Poria cum Radix Pini Rescues Barium Chloride-Induced Arrhythmia by Regulating the cGMP-PKG Signalling Pathway Involving ADORA1 in Zebrafish

Poria cum Radix Pini Rescues Barium Chloride-Induced Arrhythmia by Regulating the cGMP-PKG Signalling Pathway Involving ADORA1 in Zebrafish

The traditional Chinese medicine Poria cum Radix Pini (PRP) is a fungal medicinal material that has been proven to play an important role in the treatment of arrhythmia. However, the mechanism of its effect on arrhythmia is still unclear. In this study, network pharmacology and metabolomics correlat...

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Bibliographic Details
Main Authors: Ning-Juan Yang, Yan-Ru Liu, Zhi-Shu Tang, Jin-Ao Duan, Ya-Feng Yan, Zhong-Xing Song, Ming-Geng Wang, Yu-Ru Zhang, Bai-Jin Chang, Meng-Li Zhao, Yan-Ting Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pharmacology
Subjects:
arrhythmia
Poria cum Radix Pini
ADORA1
cGMP-PKG signalling pathway
zebrafish
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.688746/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.688746/full

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