Similar programmed death ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer
Abstract Programmed Death Ligand 1 (PD-L1) is crucial in regulating the immunological tolerance in non-small cell lung cancer (NSCLC). Alveolar macrophage (AM)-derived PD-L1 binds to its receptor, PD-1, on surveilling lymphocytes, leading to lymphocyte exhaustion. Increased PD-L1 expression is assoc...
Main Authors: | F. Polverino, D. Mirra, C. X. Yang, R. Esposito, G. Spaziano, J. Rojas-Quintero, M. Sgambato, E. Piegari, A. Cozzolino, E. Cione, L. Gallelli, A. Capuozzo, C. Santoriello, L. Berrino, J. P. de- Torres, T. L. Hackett, M. Polverino, B. D’Agostino |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-12-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-26650-9 |
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