STAT5a Confers Doxorubicin Resistance to Breast Cancer by Regulating ABCB1

STAT5a Confers Doxorubicin Resistance to Breast Cancer by Regulating ABCB1

Chemoresistance is a daunting challenge to the prognosis of patients with breast cancer. Signal transducer and activator of transcription (STAT) 5a plays vital roles in the development of various cancers, but its function in breast cancer is controversial, and its role in chemoresistance in breast c...

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Bibliographic Details
Main Authors: Zhaoqing Li, Cong Chen, Lini Chen, Dengdi Hu, Xiqian Yang, Wenying Zhuo, Yongxia Chen, Jingjing Yang, Yulu Zhou, Misha Mao, Xun Zhang, Ling Xu, Siwei Ju, Jun Shen, Qinchuan Wang, Minjun Dong, Shuduo Xie, Qun Wei, Yunlu Jia, Jichun Zhou, Linbo Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
breast cancer
STAT5A
ABCB1
pimozide
doxorubicin resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.697950/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2021.697950/full

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