Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.

Impact of HIV on CD8+ T cell CD57 expression is distinct from that of CMV and aging.

<h4>Background</h4>Chronic antigenic stimulation by cytomegalovirus (CMV) is thought to increase "immunosenesence" of aging, characterized by accumulation of terminally differentiated CD28- CD8+ T cells and increased CD57, a marker of proliferative history. Whether chronic HIV...

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Autori principali: Sulggi A Lee, Elizabeth Sinclair, Hiroyu Hatano, Priscilla Y Hsue, Lorrie Epling, Frederick M Hecht, David R Bangsberg, Jeffrey N Martin, Joseph M McCune, Steven G Deeks, Peter W Hunt
Natura: Articolo
Lingua:English
Pubblicazione: Public Library of Science (PLoS) 2014-01-01
Serie:PLoS ONE
Accesso online:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089444&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089444&type=printable

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