Histopathological Tumor and Normal Tissue Responses after 3D-Planned Arc Radiotherapy in an Orthotopic Xenograft Mouse Model of Human Pancreatic Cancer

Histopathological Tumor and Normal Tissue Responses after 3D-Planned Arc Radiotherapy in an Orthotopic Xenograft Mouse Model of Human Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers. Innovative treatment concepts may enhance oncological outcome. Clinically relevant tumor models are essential in developing new therapeutic strategies. In the present study, we used two human PDAC cell lines for an orth...

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Bibliographic Details
Main Authors: Sophie Dobiasch, Severin Kampfer, Katja Steiger, Daniela Schilling, Julius C. Fischer, Thomas E. Schmid, Wilko Weichert, Jan J. Wilkens, Stephanie E. Combs
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
image-guided high-precision radiation
stereotactic irradiation
histopathology
pancreatic cancer
preclinical tumor mouse model
small-animal radiation research platform (SARRP)
Online Access:https://www.mdpi.com/2072-6694/13/22/5656

Internet

https://www.mdpi.com/2072-6694/13/22/5656

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