A global analysis of low-complexity regions in the Trypanosoma brucei proteome reveals enrichment in the C-terminus of nucleic acid binding proteins providing potential targets of phosphorylation [version 2; peer review: 2 approved]
Background: Low-complexity regions (LCRs) on proteins have attracted increasing attention recently due to their role in the assembly of membraneless organelles or granules by liquid-liquid phase separation. Several examples of such granules have been shown to sequester RNA and proteins in an inactiv...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wellcome
2020-11-01
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Series: | Wellcome Open Research |
Online Access: | https://wellcomeopenresearch.org/articles/5-219/v2 |