The disbalance of LRP1 and SIRPα by psychological stress dampens the clearance of tumor cells by macrophages

The disbalance of LRP1 and SIRPα by psychological stress dampens the clearance of tumor cells by macrophages

The relationship between chronic psychological stress and tumorigenesis has been well defined in epidemiological studies; however, the underlying mechanism remains underexplored. In this study, we discovered that impaired macrophage phagocytosis contributed to the psychological stress-evoked tumor s...

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Bibliographic Details
Main Authors: Yanping Wu, Xiang Luo, Qingqing Zhou, Haibiao Gong, Huaying Gao, Tongzheng Liu, Jiaxu Chen, Lei Liang, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Psychological stress
Tumorigenesis
Macrophages
Phagocytosis
LRP1
SIRPα
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521002148

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http://www.sciencedirect.com/science/article/pii/S2211383521002148

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