The interferon-β/STAT1 axis drives the collective invasion of skin squamous cell carcinoma with sealed intercellular spaces

Abstract The process by which cancer cells invade as a cell cluster, known as collective invasion, is associated with metastasis and worse prognosis of cancer patients; therefore, inhibition of collective invasion is considered to improve cancer treatment. However, the cellular characteristics respo...

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Bibliographic Details
Main Authors: Yuji Kumagai, Junko Nio-Kobayashi, Seiichiro Ishihara, Atsushi Enomoto, Masashi Akiyama, Ryosuke Ichihara, Hisashi Haga
Format: Article
Language:English
Published: Nature Publishing Group 2022-05-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-022-00403-9