Hydrodynamic delivery of Cre protein to lineage-mark or time-stamp mouse hepatocytes in situ.

Hydrodynamic delivery of Cre protein to lineage-mark or time-stamp mouse hepatocytes in situ.

Cre-responsive fluorescent marker alleles are powerful tools for cell lineage tracing in mice; however their utility is limited by regulation of Cre activity. When targeting hepatocytes, hydrodynamic delivery of a Cre-expression plasmid can convert Cre-responsive alleles without inducing the intrace...

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Bibliographic Details
Main Authors: Katherine M Sonsteng, Justin R Prigge, Emily A Talago, Ronald K June, Edward E Schmidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3953374?pdf=render

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http://europepmc.org/articles/PMC3953374?pdf=render

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