Mitochondrial fission and bioenergetics mediate human lung fibroblast durotaxis
Pulmonary fibrosis is characterized by stiffening of the extracellular matrix. Fibroblasts migrate in the direction of greater stiffness, a phenomenon termed durotaxis. The mechanically guided fibroblast migration could be a crucial step in the progression of lung fibrosis. In this study, we found p...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2023-01-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.157348 |