Mutation and Diversity of Diphtheria Toxin in Corynebacterium ulcerans

Corynebacterium ulcerans infection is emerging in humans. We conducted phylogenetic analyses of C. ulcerans and C. diptheriae, which revealed diverse diphtheria toxin in C. ulcerans. Diphtheria toxin diversification could decrease effectiveness of diphtheria toxoid vaccine and diphtheria antitoxin f...

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Bibliographic Details
Main Authors: Ken Otsuji, Kazumasa Fukuda, Midori Ogawa, Mitsumasa Saito
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2019-11-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/25/11/18-1455_article