Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells

Modeling Transposition of the Great Arteries with Patient-Specific Induced Pluripotent Stem Cells

The dextro-transposition of the great arteries (d-TGA) is one of the most common congenital heart diseases. To identify biological processes that could be related to the development of d-TGA, we established induced pluripotent stem cell (iPSC) lines from two patients with d-TGA and from two healthy...

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Bibliographic Details
Main Authors: Imelda Ontoria-Oviedo, Gabor Földes, Sandra Tejedor, Joaquín Panadero, Tomoya Kitani, Alejandro Vázquez, Joseph C. Wu, Sian E. Harding, Pilar Sepúlveda
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
great arteries transposition
endothelial cells
angiogenesis
Notch signaling pathway
iPSC
Online Access:https://www.mdpi.com/1422-0067/22/24/13270

Internet

https://www.mdpi.com/1422-0067/22/24/13270

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