AGR2: a secreted protein worthy of attention in diagnosis and treatment of breast cancer

AGR2 is a secreted protein widely existing in breast. In precancerous lesions, primary tumors and metastatic tumors, the expression of AGR2 is increased, which has aroused our interest. This review introduces the gene and protein structure of AGR2. Its endoplasmic reticulum retention sequence, prote...

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Bibliographic Details
Main Authors: Ke Zhang, Yuan Li, Xiangyi Kong, Chuqi Lei, Huaiyu Yang, Nianchang Wang, Zhongzhao Wang, Hu Chang, Lixue Xuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1195885/full