Inhibitory insula-ACC projections modulate affective but not sensory aspects of neuropathic pain

Inhibitory insula-ACC projections modulate affective but not sensory aspects of neuropathic pain

Abstract The insula and anterior cingulate cortex (ACC) are brain regions that undergo structural and functional reorganization in neuropathic pain states. Here, we aimed to study inhibitory parvalbumin positive (PV+) posterior insula (pIC) to posterior ACC (pACC) projections, and to evaluate the ef...

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Bibliographic Details
Main Authors: Heloísa Alonso-Matielo, Zizhen Zhang, Eder Gambeta, Junting Huang, Lina Chen, Gabriel Oliveira de Melo, Camila Squarzoni Dale, Gerald W. Zamponi
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Molecular Brain
Subjects:
Insular cortex
Anterior cingulate cortex
Neuropathic pain
Neural projection
Optogenetics
Online Access:https://doi.org/10.1186/s13041-023-01052-8

Internet

https://doi.org/10.1186/s13041-023-01052-8

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