Molecular Subtype-Specific Expression of MicroRNA-29c in Breast Cancer Is Associated with CpG Dinucleotide Methylation of the Promoter.

Basal-like breast cancer is a molecularly distinct subtype of breast cancer that is highly aggressive and has a poor prognosis. MicroRNA-29c (miR-29c) has been shown to be significantly down-regulated in basal-like breast tumors and to be involved in cell invasion and sensitivity to chemotherapy. Ho...

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Bibliographic Details
Main Authors: Elizabeth Poli, Jing Zhang, Chika Nwachukwu, Yonglan Zheng, Babatunde Adedokun, Olufunmilayo I Olopade, Yoo-Jeong Han
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4634951?pdf=render