Identifying specific TLS-associated genes as potential biomarkers for predicting prognosis and evaluating the efficacy of immunotherapy in soft tissue sarcoma

Identifying specific TLS-associated genes as potential biomarkers for predicting prognosis and evaluating the efficacy of immunotherapy in soft tissue sarcoma

BackgroundThe tertiary lymphatic structure (TLS) is an important component of the tumor immune microenvironment and has important significance in patient prognosis and response to immune therapy. However, the underlying mechanism of TLS in soft tissue sarcoma remains unclear.MethodsA total of 256 RN...

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Bibliographic Details
Main Authors: Xiang-Xu Wang, Yun-Peng Liu, Yajie Lu, Li-Hong Wu, Jing-Yi Ren, Hongchen Ji, Xiaowen Wang, Hong-Mei Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
soft tissue sarcoma
tertiary lymphatic structure
single-cell sequencing analysis
prognosis signature
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1372692/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1372692/full

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