Normal and tumor-derived organoids as a drug screening platform for tumor-specific drug vulnerabilities

Summary: Patient-derived tumor organoids can be predictive of patient’s treatment responses, and normal tissue-derived organoids allow for drug toxicity testing. Combining both types of organoids therefore enables screening for tumor-specific drug vulnerabilities. Here, we provide a detailed protoco...

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Bibliographic Details
Main Authors: Camilla Calandrini, Jarno Drost
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721007851